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ABSTRACT Necrotizing amebic colitis is an uncommon amebiasis complication associated with high mortality. We present a case of necrotizing amebic colitis in an old patient whose diagnosis was revealed at postmortem examination. An 81-year-old man died at home without medical attention. The postmortem examination revealed ulcers involving the entire colon and intestinal perforation. The ulcers were large, geographic, and necrotizing, extending from the cecum to the rectum. The histological examination disclosed the infectious etiology by showing amebic trophozoites at the base of the ulcers. No extra-intestinal lesions were found. No information about previous episodes of dysentery or travel could be obtained. The potential role of aging or drug-causing immunosuppression and the evolution of chronic and latent intestinal infection to a severe and invasive form of amebiasis is discussed. This case reinforces the value of postmortem examination for diagnosing diseases not clinically identified.
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RESUMEN Fundamento: las enfermedades cardiovasculares constituyen la principal causa de muerte en todo el mundo, cada año mueren más personas por alguna de estas enfermedades que por cualquier otra causa. Objetivo: identificar los factores de riesgo para el desarrollo de enfermedades cardiovasculares en el reasentamiento Campo Alegre, Tierra Alta, Córdoba durante el 2020-2021. Métodos: se realizó un estudio descriptivo en el que se incluyeron a los adultos mayores de 60 años residentes en el reasentamiento. Las variables estudiadas fueron: edad, sexo, estado civil, estrato socioeconómico, nivel educativo, estado de trabajo, ingresos en el hogar o personales, antecedentes de salud, condiciones y estilos de vida saludable relacionados con la hipertensión arterial, la diabetes mellitus tipo 2, la actividad física, alimentación saludable y ración de comida diaria, control de peso, farmacodependencia, control médico e hipercolesterolemia. Se les realizó una encuesta enfocada en conocer los riesgos expuestos ante una enfermedad cardiovascular. Los datos fueron almacenados en Excel y analizados en SPSS Statistics 26. Resultados: se obtuvieron edades mínimas (60 años) y máximas (76 años y más). Se logró evidenciar que la hipertensión arterial prevalecía en la población para ambos sexos, el nivel educativo está relacionado con el nivel educativo de la población, se encontró un mayor número de casos en la población sin estudios. Conclusiones: la frecuencia de los factores de riesgo para enfermedades cardiovasculares presentes en la población, alerta sobre la necesidad de desarrollar planes de promoción y prevención de salud de las enfermedades presentes en esta zona del municipio de Tierralta, Córdoba ya que se ha evidenciado que esto conlleva a consecuencias en la calidad de vida de la población adulta mayor.
ABSTRACT Background: cardiovascular diseases are the leading cause of death worldwide, each year more people die from one of these diseases than from any other cause. Objective: to identify the risk factors for the development of cardiovascular diseases in the Campo Alegre resettlement, Tierra Alta, Córdoba during 2020-2021. Methods: a descriptive study was carried out in which adults over 60 years of age residing in the resettlement were included. The variables studied were: age and sex, marital status, socioeconomic status, educational level, work status, household or personal income, health history and healthy lifestyle conditions such as high blood pressure, type 2 diabetes mellitus, physical activity , healthy eating and daily food ration, weight control, drug dependence, medical control and hypercholesterolemia. They were given a survey focused on knowing the risks exposed to cardiovascular disease. The data was stored in Excel and analyzed in SPSS Statistics 26. Results: minimum ages (60 years) and maximum ages (76 years and over) were obtained. It was possible to show that arterial hypertension prevailed in the population for both sexes, the educational level is related to the educational level of the population, a greater number of cases was found in the population without studies. Conclusions: the frequency of risk factors for cardiovascular diseases present in the population warns about the need to develop health promotion and disease prevention plans in this area of the municipality of Tierralta, Córdoba, since it has been shown that this entails to consequences in the quality of life of the elderly population.
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Introducción: en Cuba las enfermedades del sistema cardiovascular se han considerado una de las principales causas de muerte materna, con valores muy elevados en contraposición con otros indicadores de salud. Conocer la esencia de este fenómeno es imprescindible para el manejo adecuado de las políticas que permitan disminuir este indicador. Objetivo: describir el comportamiento de la mortalidad materna en Cuba por causas cardiovasculares desde el 2013 hasta el 2019. Métodos: se realizó un estudio descriptivo longitudinal retrospectivo, que comprendió las muertes maternas por causas cardiovasculares en el período del 2013 al 2019. Se realizó un análisis de la tendencia de este indicador y una predicción del comportamiento del mismo para los años siguientes al período, a través de complementos del software Microsoft Excel. Se emplearon las tasas de mortalidad materna general y por causas como medida de resumen para el análisis estadístico. Resultados: la mortalidad materna por causas cardiovasculares tendió a la oscilación alrededor de la media en todo el período. Este indicador aumentó en un 10,3%. Las principales causas de muerte fueron las enfermedades del sistema circulatorio (65,5%) y los trastornos hipertensivos (34,2%). Se predijo un aumento de las tasas por estas causas para 2021. Conclusiones: el comportamiento de la mortalidad materna por causas cardiovasculares no tuvo un patrón específico en su tendencia, sin embargo existe una resistencia a la disminución. Se estimó un posible aumento para años venideros por lo que se recomienda una revisión de este problema por parte del Sistema de Salud. (AU)
Introduction: in Cuba diseases of the cardiovascular system have been considered one of the main causes of maternal death, with very high values in contrast to other health indicators. Knowing the essence of this phenomenon is essential for the proper management of policies that allow reducing this indicator. Objective: to describe the behaviour of maternal mortality from cardiovascular causes in Cuba since 2013 to 2019. Methods: a retrospective longitudinal descriptive study was carried out, which included maternal deaths due to cardiovascular causes in the period from 2013 to 2019. An analysis of the trend of this indicator was carried out and a prediction of its behaviour for the years following the period, through Microsoft Excel software add-ins. General and cause-based maternal mortality rates were used as a summary measure for statistical analysis. Results: maternal mortality from cardiovascular causes tended to oscillate around the mean throughout the period. This indicator increased by 10.3%. The main causes of death were diseases of the circulatory system (65.5%) and hypertensive disorders (34.2%). An increase in rates for these causes was predicted for 2021. Conclusions: the behaviour of maternal mortality due to cardiovascular causes did not have a specific pattern in its trend, however there is a resistance to the decrease. A possible increase was estimated for future years, so a review of this problem by the Health System is needed.
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Maternal Mortality , Cause of Death , Cardiovascular Diseases , CubaABSTRACT
The succession of microbiota is closely associated with several essential factors, including race, sex, health condition, lifestyle, postmortem interval, etc., and it has great potential application value in forensic medicine. This paper summarizes recent studies on the forensic applications of the microbiome, including individual identification, geographical feature identification, origin identification of the tissue or body fluid, and postmortem interval estimation, and introduces the current machine learning algorithms for microbiology research based on next-generation sequencing data. In addition, the current problems facing forensic microbiomics such as the extraction and preservation of samples, construction of standardization and database, ethical review and practical applicability are discussed. Future multi-omics studies are expected to explore micro ecosystems from a comprehensive and dynamic perspective, to promote the development of forensic microbiomics application.
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Humans , Forensic Medicine , Autopsy , Microbiota/genetics , Algorithms , High-Throughput Nucleotide Sequencing , Postmortem ChangesABSTRACT
Resumen En Patología Forense es común estudiar cadáveres de individuos con antecedente de alcoholismo crónico, que son encontrados fallecidos y cuyo deceso no fue presenciado; por lo que en gran cantidad de autopsias la determinación de la causa de muerte es compleja. La cetoacidosis alcohólica constituye un síndrome complejo derivado de una alteración del metabolismo en el contexto de un consumo excesivo de alcohol e ingesta calórica insuficiente. Se trata de un diagnóstico diferencial importante como causa de muerte en alcohólicos crónicos que fallecen posterior a un ayuno de algunos días, secundario a molestias abdominales como gastritis inducida por etanol, usualmente asociada a vómitos. Clínicamente estas personas presentan además dolor abdominal, taquicardia y alteraciones respiratorias. El diagnóstico postmortem se confirma mediante la presencia de cuerpos cetónicos, especialmente beta-hidroxibutirato, en sangre, humor vítreo u orina. A continuación se presentan tres casos de muerte súbita por cetoacidosis alcohólica con historia de abuso crónico de bebidas etílicas; se discute su fisiopatología, hallazgos al momento de la autopsia y resultados de exámenes complementarios (análisis toxicológico y estudio histopatológico).
Abstract In the forensic pathology setting, it is frequent to study corpses of individuals that were known to be chronic alcoholics and suffered a sudden death. Therefore, many autopsies are performed, in which determining the cause of death is a complex task. Alcoholic ketoacidosis refers to a complex syndrome derived from a metabolic disarrangement, related to excessive consumption of alcohol and an insufficient caloric intake. It is an important diagnosis that should be considered in sudden deaths of chronic alcoholics with a recent history of fasting, due to abdominal complains such as gastritis induced by alcohol and usually associated with recurrent vomiting. Clinically these patients present with abdominal pain, tachycardia and respiratory anomalies. The diagnosis can be confirmed when elevated ketone bodies, especially beta-hydroxybutyrate, are found in blood, vitreous humour or urine. In this paper we present three cases of sudden death by alcoholic ketoacidosis with a history of chronic abuse of alcohol, discussing it´s pathophysiology, autopsy findings and the results of additional studies (toxicologic screening and histopathology).
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Humans , Male , Female , Adult , Middle Aged , Autopsy , Ketone Bodies , Ketosis/diagnosis , Costa RicaABSTRACT
Introducción: el análisis de la mortalidad hospitalaria permite evaluar la calidad de la asistencia médica. Las últimas publicaciones sobre mortalidad en el Hospital Infantil Dr. Robert Reid Cabral datan de 1997 Objetivo: conocer el comportamiento de la mortalidad en el Hospital Infantil Dr. Robert Reid Cabral durante el periodo 20132017 Métodos: estudio descriptivo. Se revisaron los libros de registro y actas de defunciones de los pacientes fallecidos en el Hospital Dr. Robert Reid Cabral durante el periodo 20132017. Resultados: 3,800 pacientes fallecieron, en promedio 760 fallecidos por año (margen 679-868). 79.9 % con menos de 5 años de edad; las muertes en menores de 1 año de edad representaron el 61.3 % y en el periodo neonatal el 26.1 %. La Sepsis/Shock Séptico (43.4 %) y la Hemorragia Pulmonar (15.4 %) fueron los dos principales diagnósticos de defunción; el 34 % de los fallecidos presentaban una morbilidad asociada al diagnóstico de defunción y en el 40 % la morbilidad asociada era una malformación congénita. El 69.5 % fallecieron en la Unidad de Cuidados Intensivos Pediátricos o Neonatal y 40 % de los pacientes fallecieron antes de las 48 horas de su ingreso al hospital. Conclusión: el grupo etario de mayor mortalidad son los menores de 1 año de edad, se evidencia un alto porcentaje de muertes con enfermedad crónica y malformaciones congénitas asociadas. El hecho de que el 40 % de los pacientes fallecieran antes de las 48 horas de su ingreso, indica la condición de gravedad en que estos pacientes llegan al hospital
Introduction: the analysis of hospital mortality allows to evaluate the quality of medical care. The latest publications on mortality at Dr. Robert Reid Cabral Children's Hospital date from 1997. Objective: to know the behavior of mortality in the Dr. Robert Reid Cabral Children's Hospital during the period 2013-2017. Methods: descriptive study. Registration books and death certificates of deceased patients at Dr. Robert Reid Cabral Hospital during 2013-2017 were reviewed. Results: 3,800 patients died, on average 760 deaths per year (margin 679-868). 79.9 % with less than 5 years of age; deaths in children under 1 year of age represented 61.3 % and in the neonatal period 26.1 %. Sepsis / Septic Shock (43.4 %) and Pulmonary Hemorrhage (15.4 %) were the two main diagnoses of death; 34 % of the deceased had a morbidity associated with the diagnosis of death and in 40 % the associated morbidity was a congenital malformation. 69.5 % died in the Pediatric or Neonatal Intensive Care Unit and 40 % of the patients died within 48 hours of admission to the hospital. Conclusion: the age group with the highest mortality are those under 1 year of age, a high percentage of deaths with chronic disease and associated congenital malformations are evident. The fact that 40 % of patients died before 48 hours of admission indicates the serious condition in which these patients arrive at the hospital.
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Humans , Infant, Newborn , Infant , Child, Preschool , Child , Infant Mortality , Cause of Death , Shock, Septic/mortality , Congenital Abnormalities/mortality , Risk Factors , Dominican Republic/epidemiologyABSTRACT
Objective To analyze the mortality level, death causes and trend of residents in Heqing Community of Pudong New District，Shanghai，and to provide a basis for formulating disease prevention and control plans. Methods Data of death surveillance of registered population in Heqing Community, Shanghai from January 1, 2013, to December 31, 2019 were collected. Descriptive epidemiological method was used to analyze the population structure, mortality rate, death cause composition and cause order of death of the residents in Heqing Community from 2013 to 2019. Results From 2013 to 2019, the aging level of residents in Heqing Community of Pudong New District each year was much higher than the aging level (16.15%) of the Sixth National Census, and the aging level remained an increasing trend. The death rates of residents in Heqing Community, Shanghai from 2013 to 2019 were 772.62/100 000, 751.59/100 000, 814.37/100 000, 814.43/100 000, 803.64/100 000, 736.52/100 000, and 757.81/100 000, respectively. The average annual mortality rate was 778.51/100 000, and there was significant difference between the male and the female (P<0.05). From 2013 to 2019, the top four causes of death were circulatory system diseases, malignant tumors, respiratory diseases, injuries and poisonings. There were significant differences in malignant tumors and respiratory diseases between the male and the female. Conclusion The aging of residents in Heqing Community of Pudong New District was serious, and the main cause of death of the population was chronic non-communicable diseases, which suggests that local health departments need to strengthen prevention and treatment of chronic diseases, and at the same time，pay attention to other external hazards such as traffic accidents and accidental falls.
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Objective To understand the distribution characteristics of death causes and potential life loss of residents in Pudong New Area from 2009 to 2018, assess the disease burden caused by different diseases, and provide a basis for formulating regional prevention and control strategies. Methods The mortality data of residents in Pudong New Area of Shanghai from 2009 to 2018 were collected. The death causes were classified by International Classification of Diseases (ICD-10). The crude mortality rate, standardized mortality rate, potential years of life lost (PYLL), potential years of life lost rate (PYLLR), and average years of life lost (AYLL) were calculated. Results The crude mortality and standardized mortality of residents in Pudong New Area between 2009 and 2018 were 7.55‰ and 3.65‰, respectively. The top five causes of death in Pudong New Area residents were circulatory system diseases, tumors, respiratory diseases, endocrine nutrition and metabolic diseases, and injury and poisoning, accounting for 87.85% of the total deaths. The PYLL was 687 729 person-years, the PYLLR was 24.11‰ and the AYLL was 3.19 years per person. The top 5 causes of life loss of residents in Pudong New Area was tumor, circulatory system disease, injury and poisoning, endocrine nutrition and metabolism illness, and congenital anomalies, accounting for 82.08% of total life loss of residents. Conclusion Chronic non-infectious diseases, including circulatory diseases, tumors, and endocrine nutritional metabolism diseases, were the main causes of death of residents in Pudong New Area, and caused a heavy disease burden, which should be the focus of prevention and control in the future. Comprehensive preventive and control measures should be taken to protect the residents from the harm due to chronic non-communicable diseases and improve the health condition of the residents in Pudong New Area.
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Objective To explore the mortality and main causes of death of residents in Shannan City. Methods Death data in Shannan City in 2018 were collected. The data was encoded and classified according to the International Classification of Diseases (ICD-10). The 2010 standard population was used to standardize the mortality rate. Results In 2018, the mortality rate of residents in Shannan City was 359.53/100 000, and the standardized mortality rate was 421.446/100 000. The top 5 causes of death were cerebrovascular disease, heart disease, malignant tumor, respiratory disease and digestive system disease, accounting for 74.91% of the total deaths. Tuberculosis and hepatitis B were the main lethal infectious diseases, accounting for 90% of their total deaths. Conclusion Chronic non-communicable diseases were the main causes of death in Shannan City. Tuberculosis and hepatitis B among all infectious diseases are the focus of prevention. Targeted intervention measures should be taken to reduce the incidence of disease and death.
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Objective To analyze the death cases of the oncology inpatients of the First Hospital of Hunan University of Chinese Medicine (hereinafter referred to as "this hospital") during 2007-2016; To provide the basis for the prevention and treatment of cancer, prognosis improvement and rational allocation of TCM health resources. Methods The death cases of the oncology inpatients from 2007 to 2016 were analyzed by retrospective medical history method from the aspects of causes of death, hospitalization costs and survival time. Results There were 830 death cases of the oncology inpatients in the hospital during 2007-2016, with 548 males and 282 females, and the mortality rate decreased year by year. The average hospitalization costs for patients was 39 630.86 yuan, of which TCM treatment cost 6206.98 yuan (15.66%). Patients with colon cancer had the highest proportion of TCM treatment costs (20.10%), followed by lung cancer, breast cancer, and liver cancer. The top five causes of death were lung cancer, liver cancer, breast cancer, colon cancer, and rectal cancer. The sex ratio of patients who died of lung cancer was 1.61:1. The average survival time of male patients was 446.3 days, which was far lower than the 738.3 days of female patients. The cancers with long-term survival periods were cervical cancer, breast cancer, and rectal cancer. The cancers with shorter survival periods were pancreatic cancer, liver cancer, and lung cancer. Conclusion The structure of death causes of the oncology inpatients in the hospital has a certain degree of representation. The prevention and control of lung cancer, especially male lung cancer should be strengthened; TCM health resources and prevention should be utilized rationally; the prognosis of patients with liver cancer should be improved, to improve the overall survival and quality of life of patients with breast cancer or cervical cancer, which is important for the prevention and treatment of malignant tumor.
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@#Objective To analyze the early outcomes of 203 neonates with low birth weight (<2 500 g) undergoing cardiac surgery, and to analyze the causes of death during hospitalization. Methods From June 2003 to June 2017, medical records of 203 neonates with low birth weight undergoing congenital heart surgery in Guangdong General Hospital were reviewed retrospectively. There were 124 males and 79 females, including 151 premature infants. The average birth weight was 1 719±515 g, the average age at operation was 32.7±20.2 d and the average weight at operation was 1 994±486 g. The causes of death during hospitalization (including neonates given up on treatments) were analyzed. Results Totally 103 patients had pneumonia, 98 patients needed mechanical ventilation to support breathing and 26 patients needed emergency operation before operation. All patients undergoing congenital heart surgery were treated with general anesthesia with tracheal intubation, including 107 patients under non cardiopulmonary bypass (CPB) and 96 patients under CPB with a mean CPB time of 96.5±71.7 min and a mean aorta cross-clamp time of 51.8±45.5 min. The average postoperative mechanical ventilation time was 9.1±21.5 d and the average postoperative length of stay was 26.7±19.3 d. The major postoperative complications included pneumonia, anemia, atelectasis, septicemia, intrapleural hemorrhage, diaphragm paralysis and cardiac dysfunction. Twenty-nine patients died during hospitalization and the overall mortality rate was 14.3%. Four patients died in the operation room, 14 patients died 72 hours after operation and 2 patients were given up. The main causes of hospitalized death were low cardiac output syndrome, severe infection, disseminated intravascular coagulation disorder, acute renal failure and pulmonary hypertension crisis. Conclusion Overall, early cardiac surgery for low birth weight neonates is safe and effective. The difficulty of the cardiac surgery is the key to the prognosis. Strengthening perioperative management can improve the quality of operation and reduce the risk of mortality and morbidity during hospitalization.
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Se realizó un estudio descriptivo y transversal de 89 pacientes fallecidos en el Hospital Provincial Docente Dr Joaquín Castillo Duany de Santiago de Cuba, en los meses de septiembre a noviembre de 2016, con el objetivo de identificar algunos elementos biológicos y epidemiológicos presentes al momento de la muerte, así como la variabilidad en la coincidencia diagnóstica clínico-patológica. En la serie las defunciones fueron más frecuentes en las mujeres (55,0 por ciento), mientras la hipertensión arterial resultó la condición de riesgo predominante (56,0 por ciento) y la bronconeumonía la principal causa de mortalidad hospitalaria. Se observó un mayor número de muertes en los servicios clínicos (87,0 por ciento), pero la coincidencia en los diagnósticos clínico-patológicos fue más aceptable en las especialidades quirúrgicas. Finalmente, pudieron identificarse algunas condiciones de riesgo al momento de los decesos, así como diferencias diagnósticas en relación con las causas directas de muerte, que mostraron valores superiores a lo esperado, por lo cual se sugirió la revisión de determinados procesos asistenciales en dicha institución hospitalaria
A descriptive and cross-sectional study of 89 patients, who died in Dr Joaquín Castillo Duany Teaching Provincial Hospital, was carried out in Santiago de Cuba from September to November, 2016, aimed at identifying some biological and epidemiological elements present at the moment of death, as well as the variability in the clinical-pathological diagnostic coincidence. In the series, deaths were more frequent in women (55.0 percent), while hypertension was the predominant risk condition (56.0 percent) and bronchopneumonia the main cause of hospital mortality. A higher number of deaths was observed in the clinical services (87.0 percent), but the coincidence in the clinical-pathological diagnoses was more acceptable in the surgical specialties. Finally, some risk conditions could be identified at the moment of deaths, as well as diagnostic differences related to the direct causes of death that showed values higher than expected, reason why the review of certain assistance processes in this hospital institution was suggested
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Humans , Male , Female , Clinical Diagnosis , Cause of Death/trends , Diagnostic Techniques and Procedures/mortality , Pathology, Molecular , Epidemiology, Descriptive , Cross-Sectional StudiesABSTRACT
Objective To investigate the characteristics of personal injuries in motorcycle accidents in Chongqing area to provide the reliable information and reference basis for reducing the injury and death risk of the motorcycle accidents.Methods Two hundreds and thirteen cases of motorcycle traffic accident occurred in Chongqing area from January 2015 to June 2016 were deeply collected,the collected contents included the basicinformation,driver information and personal injury,etc.Then accident data were statistically analyzed.Results The death rate of motorcycle drivers was higher than that of the pillion passengers.The death causes of craniocerebral injuries and craniocerebral injuries complicating thoracic and abdominal organ injuries accounted for 58.8％ and 20 ％ respectively,the proportions of head and neck,chest and back,lower extremity,upper extremity,abdominal and pelvic part and perineal part MAIS ≥2 were 71％,59％,33％,25％,20％ and 7％ respectively.The perineal injury rate of motorcycle drivers was higher than that of the pillion passengers.The ratio of occurrence rates between lower extremity fracture to upper extremity fracture was 1.8 ∶ 1,the persons in motorcycles-trucks accidents were easier to suffer from vehicle crushing.Conclusion Head and chest injuries are important causes leading to motorcycle drivers and pillion passengers' death and injury.The perineal injury can serve as an important basis for identifying the drivers and pillion passengers in partial motorcycle accidents.
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Objective To understand the characteristics and distribution of injury related deaths in residents aged ≥60 years in Jing'an district of Shanghai and provide evidence for the prevention of injury and effective intervention in this population.Methods According to the data from diseases surveillance and death-reporting system in Jing'an during 1975-2014,the causes of 5 199 injury related deaths were analyzed.Results The average injury related mortality in the elderly aged ≥60 years in Jing'an was 159.37/100 000 during this period.The injury related mortality increased with age.Fall was the first cause of injury related death,accounting for 53.30％.The characteristics and distribution of injury related deaths varied with age and gender.Conclusion Injury has become an important cause affecting the health of the elderly.It is necessary to conducted targeted injury prevention and control in the elderly in communities.
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Objective To understand the characteristics and distribution of injury related deaths in residents aged ≥60 years in Jing'an district of Shanghai and provide evidence for the prevention of injury and effective intervention in this population.Methods According to the data from diseases surveillance and death-reporting system in Jing'an during 1975-2014,the causes of 5 199 injury related deaths were analyzed.Results The average injury related mortality in the elderly aged ≥60 years in Jing'an was 159.37/100 000 during this period.The injury related mortality increased with age.Fall was the first cause of injury related death,accounting for 53.30％.The characteristics and distribution of injury related deaths varied with age and gender.Conclusion Injury has become an important cause affecting the health of the elderly.It is necessary to conducted targeted injury prevention and control in the elderly in communities.
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Objective To understand the disease distribution and change rule of death causes by analyzing 8 670 dead cases in the First Affiliated Hospital of Southwest Medical University during Juhuary 1,2000 to December 31,2014.Methods The disease classification in 2000 and 2001 adopted the ICD-9 as the standard,which in other years adopted the ICD-10 as the standard.The medical records of dead hospitalized cases in our hospital during Juhuary 1,2000 to December 31,2014 were retrospectively analyzed by using the Excel 2007,SPSS17.0 software system.Results The sex ratio of male and female mortality was about 1.92 ∶ 1 in these 15 years,the sex ratio of heart disease death was 1.3 ∶ 1.In these 15 years,the number of hospitalized patients was increased rapidly,while the mortality rate was declined year by year.The age group of high mortality rate was 60 years old and over(4 281 cases),accounting for 49.38％.Especially heart disease patients over 60 years old accounted for 61.9％of total heart disease deaths.Followed by the age group of 45-59 years old,accounting for 20.30％.The top three causes of death were circulatory system diseases,respiratory diseases and malignant tumors.The top three causes of death in circulatory system diseases were coronary heart disease,cerebral hemorrhage and cerebral infarction.The top three causes of cardiovascular system were coronary heart disease,high blood pressure and congenital heart disease.The top three causes of respiratory disease were pneumonia,chronic obstructive pulmonary disease and respiratory failure.The top three death causes of malignant tumor were lung cancer,leukemia and liver cancer.According to the seasonal distribution,the number of deaths in winter was up to 2 362 cases,the constituent ratio was 27.24 ％.Hospitalization days,the number of hospitalization death≤1 d was up to 2 625 cases,the constituent ratio was 30.28％.Conclusion Analyzing the death causes,disease distribution and change trend of inpatients is conducive to the rational allocationof medical resources,promote the reform of hospital management programs and improve the level of clinical epidemiological research in this area.
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Objective To understand the main causes of death and the potential years of life lost (PYLL) of residents living in Yubei District of Chongqing, so as to provide evidence for disease control and health promotion. Methods The data of the death cases were classified according to ICD-10 method and were subjected to analysis by DeathReg2005 software. The characteristics of death of our population were analyzed using the following parameters: the crude mortality, proportions of death due to different reasons, order of death causes and the PYLL, etc. Results The crude death rate of residents in our study was 605.02 per 100 000 in 2012, with the standardized death rate being 440.72 per 100 000; and the mortality was higher in males than in females(χ2=227.87,P<0.001).The top five causes of deaths in order were: circular system diseases, malignant tumors, respiratory system diseases, injury and poisoning, and digestive system diseases; these 5 causes contributed to 95.15% of all death causes. The top six causes of PYLL in order were: malignant tumors, injury and poisoning, circular system diseases, respiratory system diseases, perinatal system diseases, and digestive system diseases. The main causes of death among different ages have their own characteristics. Conclusion The predominant causes of death among residents in our study include chronic non-infectious diseases (circular system diseases and malignant tumors); injuries and poisoning, especially death due to traffic accident, are the major causes among young adults. Appropriate preventive and interventional measures should be taken based on the death causes of residents.
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Objective] To analyze the death causes of malignant tumors among residents in Ouhai District of Wenzhou City and provide basis for formulating targeted intervention . [ Methods] The causes of death from 2010 to 2012 were classified according to International Classification of Diseases ( ICD-10 ) and statistically analyzed by the death cause statistical software DeathReg 2005, Excel, and SPSS13.0. [ Results] The annual average mortality of malignant tumors among residents in Ouhai District was 150.41/100 000, the standardized mortality rate was 130.02/100 000.The mortality of malignant tumors was 197.48/100 000 in males and 101.93/100 000 in females, and there was significant gender difference .The top five death causes of malignant tumors were lung cancer , hepatic carcinoma , gastric cancer , colon-rectum-anus cancer , and esophagus carcinoma .The malignant tumor death causes in different age groups were different , and the mortality rate rose with the increase of age .The potential years of life lost ( PYLL) of malignant tumor death was 14 634.5 person-years.The average years of life lost ( AYLL) and PYLL rate were 8.01 years/person and 12.05‰, respectively. [Conclusion] The first cause of death among residents is malignant tumor in Ouhai District of Wenzhou City .According to characteristics of different tumors for different population, comprehensive intervention measures should be implemented to reduce the morbidity of malignant tumors .
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Objective To analysis residents'death causes in the Three Gorges Reservoir Area,and analysis the distribution of causes of death and age,gender characteristics,therefore provide basis for governments at all levels to develop disease prevention. Methods Data for classification of death cause was analyzed by Excel 2003,according to the ICD-10 classification,the years of po-tential life lost(YPLL)was calculated by SPSS1 7.0.Results Totally 62 702 death date of resident population in Three Gorges Reservoir Area from July,2003 to December,2013 were collected.The crude death rate for males and standardized mortality rate was significantly higher than that in female;Cause of death of the top five were:circulatory system disease,respiratory system dis-ease,malignant tumor,injury and poisoning and digestive system diseases;Chronic disease was the main cause of death which ac-counting for 87.76%;years of potential life lost rate of top five were:injury and poisoning,tumor,circulatory system disease,respir-atory system diseases and perinatal diseases.Conclusion The main cause of death in Three Gorges Reservoir area is a county in the circulatory system diseases,malignant tumor,respiratory system disease,and show a younger trend.Therefore,prevent premature death has become one of the focal points of disease prevention and control.
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Objective To analysis the different causes of death among patients who underwent allogeneic hematopoietic stem cell transplantation in order to explore the disadvantageous factors which affecting the long‐term survival after transplantation . Methods The planned conditioning regimen we used was BU/Cy and associated with mobilized peripheral blood and/or bone mar‐row stem cell .Meanwhile ,we used infection prevention and GVHD control methods .Throughout the treatment we observed the death patients during the allogeneic hematopoietic stem cell transplan‐tation and posttransplant ,however ,the causes of death were retrospectively analyzed .Results Among the 35 death cases ,the reason for 11 patients were relapse ,15 with serious infection (9 cases combine GVHD ,Ⅰ - Ⅱ GVHD 3 cases ,Ⅲ - Ⅳ GVHD 6 cases) ,2 patients underwent hematopoietic failure ,2 patients died of intracranial hemorrhage ,1 patient had pulmonary edema ,1 patient sudden death ,1 patient suffered from intestinal tract because of serious GVHD ,1 patient had a progression of disease ,and 1 hemolytic crisis .With a 100 days transplantation related mortality (TRM ) was 5 .7% ,and transplantation within 100 days to 1 year of TRM was 8 .1% .We received a 3‐year and 5‐year mortality rates of 16 .2% and 16 .7% ,respectively .Conclusion Infection ,GV HD and disease relapse are the most common causes of death a‐mong patients who underwent hematopoietic stem cell transplantation .Deadly infection is commonly observed within one year after transplantation and with which accompanied by the GVHD usually .Patients associated with cGVHD have a lower rate of disease re‐lapse .